Tuesday, October 14, 2014

Fwd: Rare Genetic Disease Protects Against Bipolar Disorder; Combating Bladder Cancer With Approved Drug



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Begin forwarded message:

From: Kent Castle <kent.d.castle@hotmail.com>
Date: October 14, 2014 4:55:46 PM CDT
To: Choban Peter <peter.s.choban@aero.org>, Reason Marilou <loganlou55@yahoo.com>, Astrology Valkyrie <astrogoddess@valkyrieastrology.com>, Patterson James <w8ljz@aol.com>, Martin Bobby <bobbygmartin1938@gmail.com>, Chamberlain Sharon <sharon.m.chamberlain@saic.com>, Carman Gilbert <gil77546@sbcglobal.net>, Schwering Suanne <suannesch@mac.com>, Sutherland Aurora <fuentesd11@yahoo.com>, Bentz Jerry <bentz@sbcglobal.net>, Arnold Jenny <arnoldrj@bellsouth.net>, Brown Paul <paul.brown1@yahoo.com>, Grant Berl <berlgrant@frontier.com>, Bilger Boyd <boyd.bilger@embarqmail.com>, Books Mark <mebooks2012@gmail.com>, Lozano Marianne <kemahsabe@comcast.net>, "lrodriguez@neighborhood-centers.org" <lrodriguez@neighborhood-centers.org>
Subject: FW: Rare Genetic Disease Protects Against Bipolar Disorder; Combating Bladder Cancer With Approved Drug


 

From: reply@mail.dddmag.com
To: KENT.D.CASTLE@HOTMAIL.COM
Subject: Rare Genetic Disease Protects Against Bipolar Disorder; Combating Bladder Cancer With Approved Drug
Date: Tue, 14 Oct 2014 13:01:27 -0600

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OCT
14
Drug Discovery & Development Update
IN THIS ISSUE
  NEWS  
  Combating Bladder Cancer With Approved Drug  
  NEWS  
  Astellas Collaborates with Harvard for Retinal Degeneration Treatment  
  NEWS  
  Rats of New York and The Diseases They Carry  
  NEWS  
  Biologists Find Gene That Could Stop Tumors in Their Tracks  
  NEWS  
  Medtronic Begins Study of First Predictive Low Glucose Management Technology  

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AdvantaFlex® TPE tubing welds, seals and molds into fittings to reduce leaks. No silicone oils or animal derived components; fewer extractables than other tubing. Made in USA.

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FEATURED STORY

Rare Genetic Disease Protects Against Bipolar Disorder

Featured Story
A team of scientists led by researchers at the UMass Medical School and UMMSM have identified what is likely a key genetic pathway underlying bipolar disorder, a breakthrough that could lead to better drugs for treating bipolar affective disorder, as well as depression and other related mood disorders. Read more...

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Versatile Evaporator for Lab & Batch Processing Tasks

The Genevac Rocket Synergy Series sets a new benchmark in evaporation versatility. The system is able to dry or concentrate up to six 450ml flasks, or 18 ASE® vials, and with a simple rotor switch enable unattended automated batch processing of up to 100 litres per run.

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NEWS

Combating Bladder Cancer With Approved Drug

Thumbnail
A drug that activates targets of the hedgehog signaling pathway, which is lost when bladder cancer invades, could prevent the progression of the disease in humans. Clinical trials are planned. Read more...                  

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NEWS

Astellas Collaborates with Harvard for Retinal Degeneration Treatment

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Astellas Pharma Inc. announced a research collaboration with an investigator at Harvard focused on discovering the pathologic mechanism for retinitis pigmentosa and identification of new therapeutic targets. Read more...

FULL STORY

Biofluid miRNA Profiling: From Sample to Biomarker

Join us for a free, educational webcast, as Senior Director of Product Development, Dr. Eric Lader leads an in-depth discussion of:
• miRNA Profiling of biofluid samples
• miRNA biomarker discovery
• supporting data for sample to biomarker miRNA analysis

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NEWS

Rats of New York and The Diseases They Carry

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In the first study to look at would-be diseases carried by New York City rats, scientists at the Center for Infection and Immunity at Columbia University's Mailman School of Public Health identified bacterial pathogens, including E. coli, Salmonella, and C. difficile, that cause mild to life-threatening gastroenteritis in people. Read more...

FULL STORY
NEWS

Biologists Find Gene That Could Stop Tumors in Their Tracks

Thumbnail
The dirt in your backyard may hold the key to isolating cancerous tumors and to potential new treatments for a host of cancers. Read more...                                         

FULL STORY
NEWS

Medtronic Begins Study of First Predictive Low Glucose Management Technology

Medtronic Inc. announced that the first patients have been enrolled in an investigational device exemption (IDE) study of its breakthrough Predictive Low Glucose Management (PLGM) technology, marking a critical step toward development of an artificial pancreas in the U.S. market. Read more...

FULL STORY
Drug Discovery & Development
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Tuesday, October 7, 2014

We were the UNDISPUTED leader in Space Capabilities!! WAKE UP PEOPLE!!!!

Look at the satellites in earth orbit. Many are critical to our economy. Can we defend, repair, return them to earth as we could with the shuttle? No, No, we can not. We have wasted billions & years of effort & have placed safety above getting the job done. We destroyed shuttle capability supposedly in the name of safety which is a false conclusion -- read nasaproblems.com. We knew what needed corrected, but did not take required action. OUR failure . Look at all the capabilities we have destroyed in the name of WHAT --an erroneous conclusion---it is unsafe.

Large payload
RMS
MMU
Airlock
Runway lander
EMU capabilities
Reusable

We can not operate this way & survive . Think other countries aren't going after our space assets.
The Media will not cover, why , why ------very very damaging to America---the facts must get out. Those who care about America's future should start spreading the word using all available approaches!

Saturday, October 4, 2014

Considers body heat generated by firefighters

More on cooling suit

February 1, 2008 — Safety scientists used principles of physiology to help keep firefighters cool in the high temperature environments they often encounter. Traditional firefighting gear considers the heat of the fire, but not the body heat generated by the firefighter. By running tubes of circulating cool water close to the skin, where the body brings warm blood, the suit pulls more heat away from the body. The suit focuses on areas where the body transfers the most heat – the scalp, chest, and forearms. See also: Matter & Energy Civil Engineering Construction Weapons Technology Materials Science Physics Nature of Water Reference Firestorm Combustion Gas laws Sulfur hexafluoride Firefighters battle flames and smoke in gear that is specially designed to insulate them -- even when temperatures exceed one thousand degrees. But the very same life-saving equipment a firefighter dons may be putting him or her at risk -- by raising body temperatures to dangerous levels. Now researchers are developing a system to cool them off while they're smack dab in the middle of the fire. Firefighting is dangerously hot work. The heat from a house fire can reach over 11-hundred degrees Fahrenheit. "It causes you to build up body heat," Jon Williams, Research Physiologist at the National Institute for Occupational Safety and Health told Ivanhoe. But soon -- firefighters may add another layer of protection that will subtract body heat. This is a cooling suit -- a spandex undergarment, lined with plastic tubing. Physiologists say when a firefighter starts to work hard. His body gets rid of heat by moving warm blood into the skin. These tubes allow cool water to carry the heat away from the firefighter's body. The suit is designed to concentrate on areas where the body transfers the most heat. "The scalp, the areas of the chest, the forearms. Where you get more heat transfer in those areas than you would if you were cooling another area of the body," Williams said. At the National Institute for Occupational Safety and Health Lab, volunteers test the suit -- by walking on a treadmill -- to raise the person's core body temperature. For this test, researchers turned on the water transfer system. The volunteer's temperature barely changed. For the second test, the cooling system was not turned on. After just a few minutes, the monitor showed a temperature spike -- his body went from ninety-seven -point-seven degrees Fahrenheit to ninety-eight-point- seven. So now, scientists hope firefighters can douse flames … and keep cool all at the same time. Hotter Houses: House materials inside and out have changed dramatically over the last three decades -- most are now made from synthetic materials rather than wood or metal. So today's blazes produce two to three times as much energy as a typical fire did in 1980, and most of that energy is released as flammable gases. The invisible gases produced in a fire can be much more dangerous than the flames, especially in enclosed spaces. Newer buildings are well insulated and tightly sealed. That means gases in newer buildings can become superheated, flammable and highly mobile. The result is extreme fire behavior, marked by life-threatening backdrafts, flashovers and gas explosions. Scores of firefighters die each year because they use old outdated methods against this volatile mix of physics and fire gases. The American Industrial Hygiene Association and the National Institute for Occupational Safety and Health contributed to the information contained in the video portion of this report.

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There is a worldwide market for suit

Firemen all over the world need a suit to maintain proper body temperature. Could be efficiently done with space suit liquid cooled garment design. Google it & educate your self of the existing technology.